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ADEN

Genetics-guided antiplatelet monotherapy Vs standard early de-escalation with ticagrelor or prasugrel at 1 month after ACS in patients at risk of bleeding.

En cours

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objectif

Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome

date de réalisation

2024

nombre de patients

2468

nombre de centres participants

Multicentric trial (26 french sites)

type de financement

Public (APHP)

Référence

NCT05577988

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Correlation between the platelet reactivity, the von Willebrand factor and bleeding and thrombotic events occuring during the year following TAVI